peptide nucleic acid การใช้

• In peptide nucleic acid ( PNA ), the sugar-phosphate backbone is replaced with a protein-like backbone.
• This review highlighted many proposed syntheses for RNA and its parts in peptide nucleic acid ( PNA ).
• They may have been carried to Earth on meteorites ( see Murchison meteorite ), created at clay or peptide nucleic acid.
• Synthetic peptide nucleic acid oligomers have been used in recent years in molecular biology procedures, diagnostic assays, and degradation by enzymes.
• In 1997, he joined the board of directors of Advanced Viral Research Corporation, a biotechnology company specializing in peptide nucleic acids.
• :: SimonP, your link to " Pages Needing Attention " above goes to an article on " Peptide nucleic acid ".
• There are also entire families of Peptide nucleic acid, Threose nucleic acid and Glycerol nucleic acid that are candidates for this kind of behavior.
• Together with Stanley Miller, Orgel also suggested that peptide nucleic acids-rather than ribonucleic acids-constituted the first pre-biotic systems capable of self-replication on early Earth.
• More specifically, telomere-peptide nucleic acid fluorescein probes are frequently used to identify telomeric sequence repeats on mitotic metaphase and interphase or meiotic pachytene-stage chromosomes.
• Another, called peptide nucleic acid, has the same chemical backbone as proteins but with nucleic acid bases in place of protein's usual amino acid side-chains.
• Pyranosyl-RNA and peptide nucleic acid may be promising candidates, but no one yet knows if their spontaneous formation is any more plausible than that of RNA.
• Artificial nucleic acids include peptide nucleic acid ( PNA ), Morpholino and locked nucleic acid ( LNA ), as well as threose nucleic acid ( TNA ).
• Both pyranosyl-RNA and peptide nucleic acid display the behavior to be expected of a genetic molecule, such as linking together in double chains like the double helix of DNA.
• The chromatin-binding region was functionally mapped and evaluated by using an approach for studying noncoding RNA function in living cells called peptide nucleic acid ( PNA ) interference mapping.
• The functional role of the Xist transcript was first definitively demonstrated in mouse female ES cells using a novel antisense technology, called peptide nucleic acid ( PNA ) interference mapping.
• Since there is no need for RNase H recognition, this can include chemistries such as 2'- O-alkyl, peptide nucleic acid ( PNA ), locked nucleic acid ( LNA ), and Morpholino oligomers.
• For example, RNA interference can be controlled using light and also patterning of gene expression has been performed in cell monolayer and in zebrafish embryos using caged morpholino or peptide nucleic acid demonstrating the control of gene expression spatiotemporally.
• Another is the heteroduplexes formed when non-natural analogs of nucleic acids are used to bind with nucleic acids; these heteroduplexes result from performing antisense techniques using single-stranded peptide nucleic acid, 2'- O-methyl phosphorothioate or Morpholino oligos to bind with RNA.
• The hypothesized existence of an RNA world does not exclude a " Pre-RNA world ", where a metabolic system based on a different nucleic acid is proposed to pre-date RNA . A candidate nucleic acid is peptide nucleic acid ( PNA ), which uses simple peptide bonds to link nucleobases.